Creative Commons Attribution/Share-Alike License; (organic chemistry, of a sugar) Lacking two hydroxyl groups. [ -nookle-o-sd] any of a group of synthetic nucleoside analogues, several of which are used as antiretroviral agents. We and our partners use cookies to Store and/or access information on a device. Each tube contains a mixture of the four nucleotides (A, G, C, and T), which acts as a substrate for DNA polymerase. Enter two words to compare and contrast their definitions, origins, and synonyms to better understand how those words are related. Chain-termination DNA sequencing, also called the dideoxynucleotide procedure, is based on the principle that during DNA synthesis, addition of a nucleotide triphosphate requires a free Crowdsourced audio pronunciation dictionary for 89 languages, with meanings, synonyms, sentence usages, translations and much more. Translations of dideoxynucleotide Chinese : Translate this Nucleotide is a derived term of deoxynucleotide. dideoxyribonucleotide. To view the purposes they believe they have legitimate interest for, or to object to this data processing use the vendor list link below. Dideoxynucleotide. These lengthy names are commonly dideoxynucleotide pronunciation - How to properly say dideoxynucleotide. Text is available under the Creative Commons Attribution/Share-Alike License; additional terms may apply.See Wiktionary Terms of Use for details. Since you have exceeded your time limit, your recording has been stopped. https://medical-dictionary.thefreedictionary.com/dideoxynucleoside, any of a group of synthetic nucleoside analogues, several of which are used as, The PC12 cell as a model for studies of the mechanism of inducing of peripheral neuropathy by anti-HIV-l, In vitro models to predict the in vivo mechanism, rate and extet of placental transfer of, Lamivudine (3TC), the negative enantiomer of 2'-deoxy-3'thiacytidine, is a, Assay-specific deoxynucleoside triphosphates (dATP, dGTP, dTTP; Amersham) and, Therefore, in that study, a very short extension strategy using alternating deoxynucleoside triphosphates (dNTPs) and, Primer extension reactions were carried out in a 20-micro]L volume containing 50 ng of input PCR product and 0.75 [micro]M primer, 25 [micro]M each of the, Our strategy for detecting the splice variants expressed from the genes is based on the extension of gene-specific minisequencing primers with fluorescent, DNA polymerase extends it by adding one fluorescently labeled, Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus, The primer extension reaction was performed using modified thermostable DNA polymerase in the presence of, Dictionary, Encyclopedia and Thesaurus - The Free Dictionary, the webmaster's page for free fun content, Cardiovascular disease in human immunodeficiency virus-infection as a cause of hospitalization: a case-series in a General Hospital in Peru, Arsenic inhabits neurite outgrowth by inhibiting the LKB1-AMPK signaling pathway, Efectos del foscarnet sobre la rata prenada, Lamivudine for chronic hepatitis B: a brief review, MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms, Determination of SMN1/SMN2 gene dosage by a quantitative genotyping platform combining capillary electrophoresis and MALDI-TOF mass spectrometry, Detection of alternatively spliced transcripts in leukemia cell lines by minisequencing on microarrays, Reliable detection of [beta]-Thalassemia and G6PD mutations by a DNA microarray, A model of cognitive decline and suicidal ideation in adults aging with HIV, Identification of pathogens by mass spectrometry. They are also known as 2',3' because both the 2' Manage Settings Continue with Recommended Cookies. This group is needed for the next nucleotide to Rate the pronunciation difficulty of dideoxynucleotide. You can try again. or post as a guest. Subscribe to learn and pronounce a new word each day! Register Listen to the audio pronunciation in several English accents. Keep up. biochemistry a nucleotide in which two hydroxyl groups have been substituted by hydrogen Collins English Dictionary. chain-terminating precursors of DNA synthesis that block further polymerization when added to the end of the DNA strand by DNA polymerase. Dideoxynucleotides. As a noun ddNTP is abbreviation of dideoxynucleotide triphosphate|lang=en. dideoxyribonucleotide. Check out these Famous cuisines around the World. Dideoxy is a derived term of ddntp. Since deoxyribose already lacks a 2'-OH, dideoxyribose lacks hydroxyl You can contribute this audio pronunciation of dideoxynucleotide to HowToPronounce dictionary. Log in or The consent submitted will only be used for data processing originating from this website. Dideoxynucleotides, or ddNTPs, are nucleotides lacking a 3'-hydroxyl (-OH) group on their deoxyribose sugar. All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. As nouns the difference between deoxynucleotide and nucleotide is that deoxynucleotide is any nucleotide that contains a Congrats! Add synonyms Learn more about the word "dideoxynucleotide" , its origin, alternative forms, and usage from Wiktionary. They are the monomeric units of the informational biopolymer, deoxyribonucleic acid ( DNA ). Congrats! Miller-Keane Encyclopedia and Dictionary of Medicine, This group is needed for the next nucleotide to As an adjective dideoxy is lacking two hydroxyl groups. You've got the pronunciation of dideoxynucleotide right. Please Word of the day - in your inbox every day, 2023 HowToPronounce. Biology Glossary search by EverythingBio.com. {{app.userTrophy[app.userTrophyNo].hints}}. Unfortunately, this browser does not support voice recording. Unfortunately, this device does not support voice recording, Click the record button again to finish recording. Dideoxynucleotides are chain-elongating inhibitors of DNA polymerase, used in the Sanger method for DNA sequencing. It's a nucleotide that is mainly used for the analysis of DNA and it helps in producing DNA strands. Seems like your pronunciation of dideoxynucleotide is not correct. As nouns the difference between dideoxynucleotide and deoxynucleotide is that dideoxynucleotide is any nucleotide formed from a deoxynucleotide by loss of a second The dideoxynucleoside analog drugs didanosine (ddI), zalcitabine (ddC), and stavudine (d4T) are the most peripheral neurotoxic drugs leading to painful (or painless) sensory neuropathies. Examples of dideoxynucleotide in a sentence, Are you a foodie? A deoxyribonucleotide is a nucleotide that contains deoxyribose. All Rights Reserved, {{app['fromLang']['value']}} -> {{app['toLang']['value']}}, Pronunciation of dideoxynucleotide with 2 audio pronunciations. If you would like to change your settings or withdraw consent at any time, the link to do so is in our privacy policy accessible from our home page.. a modified deoxyribonucleotide that lacks the 3' hydroxyl (3'-OH) group of the SUGAR component, DEOXYRIBOSE. Oops! components of DNA, containing the phosphate, sugar and organic base; when in the triphosphate form, they are the precursors We recommend you to try Safari. Dideoxynucleotides, or ddNTPs, are nucleotides lacking a 3'-hydroxyl (-OH) group on their deoxyribose sugar. Each deoxyribonucleotide dideoxynucleoside. They are 2'-deoxyadenosine 5'-triphosphate; 2'-deoxyguanosine 5'-triphosphate; 2'-deoxycytidine 5'-triphosphate; and 2'-deoxythymidine 5'-triphosphate. is that dideoxynucleotide is (biochemistry) any nucleotide formed from a deoxynucleotide by loss of an a second hydroxy group from the deoxyribose group while nucleotide is (biochemistry) Since deoxyribose already lacks a 2'-OH, dideoxyribose In automated sequencing, the ddNTPs are labeled Each tube also contains one of the four chain-terminating Record the pronunciation of this word in your own voice and play it to listen to how you have pronounced it. a modified deoxyribonucleotide that lacks the 3' hydroxyl (3'-OH) group of the SUGAR component, DEOXYRIBOSE. We and our partners use data for Personalised ads and content, ad and content measurement, audience insights and product development. Some of our partners may process your data as a part of their legitimate business interest without asking for consent. You have earned {{app.voicePoint}} points. Labeling either the DNA sequencing primers or the individual nucleotides with a radioactive or fluorescent tag enables this visualization. Copyright HarperCollins Publishers Examples of This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. An example of data being processed may be a unique identifier stored in a cookie.