Merck & Co., Inc The DOJ said the former employee and his close friend sold their Pfizer call options at "significant profits" totaling more than $350,000. Just first on for vaccine franchise, as we think about the competitive landscape. Chris, as you mentioned, we have a goal of $25 billion in risk adjusted you by 2030, and I should remind everyone that is a 2030 goal. Maybe just to add to your question specifically about the adult portfolio, I really do believe that, this plays into our sweet spot. Yes. We are extremely excited about the RSV vaccine and we'll provide data on co-administration of that vaccine with the advent of flu. Thank you. Pfizer Earnings Yes, thank you very much. Earnings Call Transcript We do expect that if there are successful combinations with flu that will drive the fluctuation of the corporate vaccine much higher, as you know, in our estimations will be expect, for example, in the U.S. around 24%, 25%, in the next few years of COVID vaccine. So having said that, we expect because of that we should get ourselves back more balanced into the three pillars, again, reinvesting back in our business, growing our dividend and doing a value enhancing share repurchases. CI Transcript : Pfizer Inc. - Thank you for your question. So with that, I think, gave me also team a good segue to close. So, after April, we continue to have Paxlovid available and but it will be assessed through an out of pocket payment mechanism. First and foremost, it's going to be about compelling science that we can add value to. And although cross-trial comparisons cannot be made, these results, in combination with the emerging objective response rate and PSA50 response, are supportive of the contribution of our EZH2 inhibitor candidate in driving these responses. And still we are not close, so I can make any comment on that. 2009 / 2:00PM GMT THOMSON REUTERS STREETEVENTS | www.streetevents.com | Contact Us 2009 Thomson Reuters. So, there is a big gap. All earnings call transcripts on Pfizer Inc. (PFE) stock. Within urogenital, prostate cancer is an area in which we have strong momentum. Materials for this call and other earnings related materials are on the Investor Relations section of pfizer.com. As a result, we expect that we will have more infections and that will drive more use of Paxlovid. So that plays also a key role in the uptake with the vaccine. We can't give now guidance for a particular product in a particular country. We have done a tremendous amount of work, as it pertains to retailers and making sure that, we have our distribution and our supply chain, well-oiled and the ability to be able to supply and to vaccinate to administer these products at both at a physical site, like a retailer or even in the case of Paxlovid getting telehealth and sort of remote health capabilities set up. We expect you to be available and generalize to all flu vaccines. Clearly, we are also concerned at the same time with provisions that would like to reduce the exclusivity of data and other provisions. On a total company basis, we continue to expect revenues of $67 billion to $71 billion, reflecting an operational decline of 31% at the midpoint. So, it's not enough to save the world. So good launch, we expect the publication of the MMWR likely to happen beginning of the next year. William, would you like to take TALAPRO part question? We are seeing the outcomes on our end. And the real question there is that I know you when you provide guidance in the beginning of the year. And if that positive, that would increase the eligible population by another 10,000 to 12,000. That's also going to contribute growth in the 25 to 30 period and take lots of things into consideration, including the impact on the P&L profile. Results showed significant and clinically meaningful improvement across the all-comers population in radiographic progression free survival, or rPFS, in men with metastatic castration resistant prostate cancer, with or without homologous recombination repair or HRR gene mutations. And we think in general that you will see an evolution in the adult market with simplified vaccination schedule, and your revaccination of COVID flu RSV. That would be great. Your line is open. Pfizer (symbol PFE) 04, 2021 Here's all with the focus of growing our business from both from a top line perspective and importantly from a bottom line perspective. We have had COVID. And notably, we did get prior to review and we're currently in registration. But this is a curable disease. So quickly, do you see this market developing? In the first three months of 2023, we have invested $2.5 billion in internal R&D and returned $2.3 billion to shareholders via our quarterly dividend, and importantly, allocated approximately $43 billion for the proposed Seagen acquisition. Given the competitive nature of the field, you're late to market and the cost of running CVOT trials in this setting. So stay tuned. Thanks very much. Recent positive study results further strengthen our franchise, building upon the global standard of care set by XTANDI, and underscoring our long-standing commitment to the pursuit of breakthroughs that define new standards of care in prostate cancer. Thank you there. So, I think in this regard because it's a new disease or a highly undeserved disease, I think education and awareness, education at the level of the prescriber, the patient, but also with the payers is going to be key to our ability to access this market. Overall, we are in the midst of an 18-month period in which we expect to launch up to 19 potential new products and indications. Yes, we can include part of -- included our estimation of how these negotiations will end up in our guidance. Dave, do you want to take the margin improvements and then Angela, a combination of products. What is your team believe just hitting CDK4 allows you to improve on hyper-intense efficacy? In addition, we have continued to grow our dividend. Comirnaty is the most utilized mRNA vaccine in the markets in which we You anticipated some of that, but so far as the negotiating reach to the guidance as a negotiation that finalized in that? So first one a few days ago, you saw the FDA advisory committee vote on Lynparza's PROpel trial. And I think on all of those counts, Pfizer is a winner. Transcript And the other question I have is more about your demand chart for Paxlovid and vaccinations both, it seems like you are assuming both Paxlovid and vaccination, utilization going up into time 24 plus timeframe? So in that aspect, the launch already has started from our side at least. Our RSV-Flu co-administration study met its primary endpoint, demonstrating non-inferiority for all four flu strains and RSV A and B strains. Pfizer Inc. (PFE) Earnings Transcripts | Seeking Alpha And we want to be very good stewards of that. And do you worry at all about vaccine fatigue? We recently presented data from our Phase 3 EMBARK study evaluating XTANDI plus leuprolide in men with non-metastatic hormone-sensitive prostate cancer with high-risk biochemical recurrence at the American Urological Association's 2023 Annual Meeting. Transcript : Pfizer Inc., Q1 2023 Earnings Call, May 02, 2023 02/05. Thank you. And we're seeing that consistent great metrics as it pertains to Nurtec. Today Id like to start off with one of the four pillars of our oncology portfolio, which are breast, urogenital, blood cancers and precision medicine. And I think that has really paid off. And we think that will open up a very large place. Pfizer (PFE) Q1 2023 Earnings Call Transcript - MSN The two individuals sold their Pfizer call options at significant profits totaling more than $350,000, the DOJ said. Your line is open. The CI Transcript : Pfizer Inc. - Shareholder/Analyst Call 27/04. And as Dave mentioned earlier, our priority right now is ensuring that we close out and successfully integrate the Seagen transaction, as well as drive value from the other deals that we've done and will continue to actively look for opportunities. When is Pfizer's next earnings announcement? Joining for the Q&A session, we also have Angela Hwang, Chief Commercial Officer and President, Global Biopharmaceuticals Business; Aamir Malik, our Chief Business Innovation Officer; Dr. William Pao, our Chief Development Officer; and Doug Lankler, our General Counsel. Maybe first of all, [indiscernible] in the upcoming data. Pfizer But suffice to say that, the price ranges that we have brought to our payers together with the value arguments that we have been able to develop through robust real world evidence from the number hospitalizations, the number of deaths that we have been able to avert through the treatment with Paxlovid is very much supportive of the pricing ranges that we are talking about. Thank you. Hopefully, we'll be late to this for to share an update. Your line is open. You know, we are very pleased what we see so far the totality, date of our few mRNA. Materials for this call and other earnings related materials are on the Investor Relations section of pfizer.com. And for us, in particular, given the profile of elranatamab, what we think is the greatest opportunity for us is in earlier lines of treatment where there has not been as much transmit, right? The study met its primary endpoint with statistically significant and clinically meaningful improvement in metastasis-free survival, with a 58% reduction in risk for radiographic progression or death. And then from M&A perspective, we are still active in the M&A market. Right now, we don't. Through the last several years, both from or the Prevnar franchise for vaccinating adults throughout work in COVID, we have learned that, the clinical profile is one thing, but you really need reliable supply, you need a commercial infrastructure, you need a great ability to educate, raise awareness and drive people to vaccination. Maybe later this year or possibly early next year and cherry pick the winner here. Press Release EPS of $1.23 beats by $0.24 | Revenue of $18.28B ( When is Alcoa's next earnings announcement? We have at least 30 minutes for Q&A. Now as regards to the frustration, for the 2023, clearly, I believe that the stock price right now does not reflect the value that half Pfizer has. I think you have seen us collaborate with the biotech ecosystem lots of different ways, and Pfizer IGNITE is another way in which we can effectively do that. Pfizer Inc. (NYSE:PFE) Q1 2023 Results Conference Call May 2, 2023 10:00 AM ET, Dr. Albert Bourla - Chairman and Chief Executive Officer, Dr. Mikael Dolsten - President, Worldwide Research, Development and Medical, Angela Hwang - Chief Commercial Officer and President, Global Biopharmaceuticals Business, Aamir Malik - Chief Business Innovation Officer, Dr. William Pao - Chief Development Officer. Transcript : Pfizer Inc., Q1 2023 Earnings Call, May 02, 2023 02/05. So I think you said '26 and I would certainly hope we'd be ahead of that. As you know, we have reported out very high antibody titers to A, similar or possibly lower to the B antigens versus standard flu vaccines. Can you talk about your next gen CDK4 program? We do think that could offer a unique profile for flu and the tolerability with our dose is very encouraging. Yes. In that the committee voted against the approval in all-comers. Your line is open. So all of these capabilities, many of them, in fact, have been underway throughout the entire time of the pandemic. And so yes, we are anticipating that there's going to be a big bolus of revenue because, first of all, if you think about Prevnar 20 Peds, that is going to be a conversion from Prevnar 20 Peds and Prevnar 13 today has a significant market share, right, in the pediatric pneumococcal, is 80% margin share. And we have already approved for the adults and then we are expecting approval for the maternal. Just wondering if you can offer your high-level perspective on how you see that frontline landscape evolving? So, that's why we believe that the combination between flu and COVID will arise also to the COVID. It is our expectation that, as we integrate Seagen in either late '23 or '24, early '24, we will begin to see margin improvement, and that will happen as we continue to improve our performance from a top-line perspective. As such, we expect our non-COVID revenues to grow at a faster rate in the second half of the year than in the first. This suggests the RSV vaccine candidate, if approved, could be co-administered with flu vaccinations and add an important component of seasonal protection against respiratory pathogens. Our next question will come from Akash Tewari with Jefferies. And so if you look at, I guess a good analog for that would be our Prevnar 20 adult launch, which was the conversion of the Prevnar 20 adult launch, and there it went really well. Pfizer (PFE) Q4 2022 Earnings Call Transcript | The And so, we look forward to having a growing and a very robust respiratory portfolio that really leverages off of this incredible commercial machinery. PFE Earnings Call - Final Transcript July 28, 2021 Pfizer, Inc. ( NYSE: PFIZER Before we begin the call, I wanted to remind you of some of some logistical items. We have strong momentum with our RSV vaccine candidate, having received a positive VRBPAC Committee vote supporting potential approval to help combat RSV in older adults and PDUFA dates for our Older Adult and Maternal indications in quick succession in the coming months. Mikael, I think both questions can go to you. Transcript : Pfizer Inc., Q4 2022 Earnings Call, Jan 31, 2023. Since 2022, we've invested approximately $70 billion, including Seagen, in business development. During the first quarter, more than 250 million patients were treated with our medicines and vaccines. And we intend to continue to work with the public and with the Chinese Government to ensure its access. CI Transcript : Pfizer Inc., Q3 2022 Earnings Call, Nov 01, 2022 01/11. And for diabetes patients, of course, it's about having a very strong HbA1c lowering maybe 2% or even more. Thank you, Chelsea. Even today, the consensus stock is down a little bit. First, could you discuss the Paxlovid private market sales potential in China, after March 31st that isn't included in your Paxlovid guidance for the year? We with the deals that we have done have remaining balance of less than $5 billion against that goal. Pfizer (PFE) Q3 2020 Earnings Call Transcript. View the latest PCTY earnings date, analysts forecasts, earnings history, and conference call transcripts. Thanks so much for the question. So, those have begun. So, I don't think there will be much fluctuation over there in the price given the longevity of the product and the contracts expire prices option will be adjusted. On the Seagen trial on Pfizer EV--302, I know there's been a huge emphasis on cohort K, which is at this time ineligibles. Today, Nurtec is the leading product in the oral CGRP class with over 47.5% market share. We have done a lot of educational efforts and there are a lot of investments that we are doing in that field. Thank you. Umer, can you repeat the question, I'm not sure we understood it.
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